acetaminophen and oxycodone | Cigna (2024)

FAQs

What is the combination of oxycodone and acetaminophen? ›

Oxycodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time.

When oxycodone/acetaminophen is swallowed, it gets absorbed by your body. It will begin working to relieve pain in about 15 to 30 minutes, although it reaches its peak effect in 1 hour. It will continue to work for 3 to 6 hours.

Oxycodone and acetaminophen tablets can make you sleepy, dizzy, or lightheaded. Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. Using products containing alcohol during treatment with oxycodone and acetaminophen tablets may cause you to overdose and die.

The findings of this randomized, double-blind clinical trial suggest that there are no clinically nor statistically significant differences in analgesic efficacy or side effects between oxycodone/acetaminophen (5 mg/325 mg) and codeine/acetaminophen (30 mg/300 mg) for outpatient treatment of acute musculoskeletal ...

Carfentanil: Carfentanil, a synthetic opioid, is a 100-fold stronger version of fentanyl. It has 5,000 times the potency of heroin and 10,000 times the potency of morphine. There has been an increase in the amount of carfentanil in narcotics, and this substance nearly invariably results in overdose and death.

Neither medication is more effective than the other, although the acetaminophen in Percocet affects different receptors than oxycodone in the pain pathway. The choice of medication depends on the type of pain and the health of the individual.

One key difference is that oxycodone is more potent than hydrocodone. This means that it takes less oxycodone to produce the same effects as hydrocodone. Oxycodone is also more likely to be abused than hydrocodone because it produces stronger effects. This also means that oxycodone has a higher risk of overdose.

It is a relatively potent drug for moderate-to-severe pain control in postoperative patients, patients with trauma, or patients with cancer. The combination of hydrocodone with acetaminophen is much more efficacious in several randomized studies without any significant changes in adverse effects.

This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

In many situations where oxycodone is prescribed, it is likely that morphine or a weaker opioid, in combination with paracetamol would be a more appropriate option.

Is OxyContin the same as oxycodone? ›

Oxycodone is marketed alone as OxyContin® in 10, 20, 40 and 80 mg extended-release tablets and other immediate-release capsules like 5 mg OxyIR®. It is also marketed in combination products with aspirin such as Percodan® or acetaminophen such as Roxicet®. How is it abused? Oxycodone is abused orally or intravenously.

Is Tramadol or Oxycodone More Effective? Both tramadol and oxycodone are effective drugs for treating pain. However, because oxycodone is so much more potent than tramadol, it is more effective for more severe pain.

Oxycodone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain. Oxycodone is also available in combination with acetaminophen (Oxycet, Percocet, others) and aspirin (Percodan).

Acetaminophen and codeine (Tylenol® with Codeine Phosphate) is a combination medicine made up of codeine (an opioid medication) and acetaminophen (a non-opioid medication) and is used to relieve pain.

The bottom line

Oxycodone (Roxicodone, Oxycontin) and oxycodone / acetaminophen (Percocet) are both opioid medications that contain oxycodone. Both are FDA approved to treat pain that's not relieved by non-opioid medications.